KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSK
All Species:
41.82
Human Site:
Y304
Identified Species:
76.67
UniProt:
P41240
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41240
NP_001120662.1
450
50704
Y304
D
V
C
E
A
M
E
Y
L
E
G
N
N
F
V
Chimpanzee
Pan troglodytes
XP_001138005
450
50665
Y304
D
V
C
E
A
M
E
Y
L
E
G
N
N
F
V
Rhesus Macaque
Macaca mulatta
XP_001101430
450
50702
Y304
D
V
C
E
A
M
E
Y
L
E
G
N
N
F
V
Dog
Lupus familis
XP_853247
465
51967
Y319
D
V
C
E
A
M
E
Y
L
E
G
N
N
F
V
Cat
Felis silvestris
Mouse
Mus musculus
P41241
450
50595
Y304
D
V
L
E
A
M
E
Y
L
E
G
N
N
F
V
Rat
Rattus norvegicus
P32577
450
50728
Y304
D
V
C
E
A
M
E
Y
L
E
G
N
N
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P41239
450
50733
Y304
D
V
C
E
A
M
E
Y
L
E
A
N
N
F
V
Frog
Xenopus laevis
NP_001079062
450
50789
Y304
D
V
S
E
G
M
E
Y
L
E
S
N
N
F
V
Zebra Danio
Brachydanio rerio
NP_001071067
450
50999
Y304
D
V
C
K
A
M
E
Y
L
E
A
N
N
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731611
1052
113728
Y908
D
T
A
S
G
M
E
Y
L
E
A
K
K
V
V
Honey Bee
Apis mellifera
XP_393399
493
55500
Y345
D
T
C
A
G
M
A
Y
L
E
S
R
H
V
V
Nematode Worm
Caenorhab. elegans
NP_001021778
539
60138
Y393
D
I
C
Q
G
M
C
Y
L
E
S
K
Q
I
V
Sea Urchin
Strong. purpuratus
XP_795344
763
85563
E623
C
N
G
M
A
Y
L
E
E
K
E
F
V
H
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
99.7
95.4
N.A.
98.4
98.4
N.A.
N.A.
93.3
83.7
85.7
N.A.
26.6
48.2
43.4
36.8
Protein Similarity:
100
98.4
100
96.1
N.A.
99.3
99.7
N.A.
N.A.
95.3
90.4
93.1
N.A.
32.7
62.8
57.3
45.7
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
93.3
80
86.6
N.A.
46.6
46.6
46.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
93.3
80
93.3
N.A.
46.6
53.3
60
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
70
0
8
0
0
0
24
0
0
0
0
% A
% Cys:
8
0
70
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
93
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
62
0
0
77
8
8
93
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
70
0
% F
% Gly:
0
0
8
0
31
0
0
0
0
0
47
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
8
0
16
8
0
0
% K
% Leu:
0
0
8
0
0
0
8
0
93
0
0
0
0
0
0
% L
% Met:
0
0
0
8
0
93
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
70
70
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% R
% Ser:
0
0
8
8
0
0
0
0
0
0
24
0
0
0
0
% S
% Thr:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
70
0
0
0
0
0
0
0
0
0
0
8
16
93
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _